Diarrhea caused by Clostridiodes (formerly Clostridium) difficile infections is on the rise among children; one population-based study found a 12.5-fold increase in incidence from 1991 to 2009. For reasons that aren't clear, C. difficile is more frequently striking children without the usual risk factors, such as hospitalization or antibiotic exposure. One thing that is known is that C. diff disease is associated with an altered intestinal microbiota.
* This article was originally published here