Tuesday, 13 August 2019

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Pinpointing the molecular mechanisms of ageing

Although each and every one of us goes through it, ageing is a poorly understood process. Researchers have used a biomarker called the epigenetic clock to identify a gene that is closely linked to ageing in humans. The study, published in Genome Biology, shows that the epigenetic clock could be a good tool for improving our understanding of the molecular mechanisms behind ageing.

source https://phys.org/news/2019-08-molecular-mechanisms-ageing.html

RTS,S vaccine could favor the acquisition of natural immunity against malaria

The RTS,S malaria vaccine could enhance the production of protective antibodies upon subsequent parasite infection, according to a study led by the Barcelona Institute for Global Health (ISGlobal), an institution supported by "la Caixa." The results, published in BMC Medicine, identify the antigens (or protein fragments) that could be included in future, more effective multivalent vaccines.

source https://medicalxpress.com/news/2019-08-rtss-vaccine-favor-acquisition-natural.html

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What's more powerful, word-of-mouth or following someone else's lead?

Researchers from the University of Pittsburgh, UCLA and the University of Texas published new research in the INFORMS journal Marketing Science (Editor's note: The source of this research is INFORMS), that reveals the power of word-of-mouth in social learning, even when compared to the power of following the example of someone we trust or admire. The same research found, however, that both word-of-mouth and following someone else's lead are two of the most powerful dynamics in influencing others through social learning.

source https://phys.org/news/2019-08-powerful-word-of-mouth.html

NASA sees wide center in tropical storm Krosa

NASA's Aqua satellite passed over the Northwestern Pacific Ocean and captured a good shot of the wide, ragged center of circulation in Tropical Storm Krosa.

source https://phys.org/news/2019-08-nasa-wide-center-tropical-storm.html

Anti-viral immune discovery could lead to better vaccines

Walter and Eliza Hall Institute researchers have identified a molecular switch that impacts immune responses to viral infections, and whether or not protective antibodies are produced.

source https://medicalxpress.com/news/2019-08-anti-viral-immune-discovery-vaccines.html

Foraging for information: Machine learning decodes genetic influence over behavior

Mice scurry around while foraging for food, but genetics may be the unseen hand controlling these meandering movements. Researchers at University of Utah Health are using machine learning to draw links between genetic controls that shape incremental steps of instinctive and learned behaviors. The results are available online in Cell Reports on August 13.

source https://medicalxpress.com/news/2019-08-foraging-machine-decodes-genetic-behavior.html

Preclinical research suggests anti-cancer effect of keto diet

It's well known that keeping blood glucose levels in check can help individuals avoid or manage diabetes, but new research led by biologists at The University of Texas at Dallas suggests that restricting blood glucose levels might also keep certain cancers at bay.

source https://medicalxpress.com/news/2019-08-preclinical-anti-cancer-effect-keto-diet.html

Finding a cosmic fog within shattered intergalactic pancakes

To understand the most ordinary matter in the universe—and the extraordinary things that happen to it—a Yale-led team of astronomers took a deep dive into the cosmic fog.

source https://phys.org/news/2019-08-cosmic-fog-shattered-intergalactic-pancakes.html

New water-beetle species show biodiversity still undiscovered in at-risk South American habitats

Researchers from the University of Kansas have described three genera and 17 new species of water scavenger beetles from the Guiana and Brazilian Shield regions of South America, areas seen as treasure houses of biodiversity. The beetles from the countries of French Guiana, Suriname, Brazil, Guyana and Venezuela were discovered through fieldwork and by combing through entomological collections at the Smithsonian Institution and KU.

source https://phys.org/news/2019-08-water-beetle-species-biodiversity-undiscovered-at-risk.html

A leap forward in kidney disease research: Scientists develop breakthrough in vitro model

Kidneys work to constantly filter blood and remove toxins from the body. Conditions such as chronic kidney disease (CKD) are characterized by a reduced ability to perform this essential function. CKD incidence is growing and more than 1.4 million individuals depend on dialysis or kidney transplant for survival. Development of new treatments requires an understanding of the mechanisms of the disease progression, but scientists have not been able to accurately model kidney filtration in vitro - until now.

source https://medicalxpress.com/news/2019-08-kidney-disease-scientists-breakthrough-vitro.html

Satellite study reveals that area emits one billion tonnes of carbon

A vast region of Africa affected by drought and changing land use emits as much carbon dioxide each year as 200 million cars, research suggests.

source https://phys.org/news/2019-08-satellite-reveals-area-emits-billion.html

Growth of wind energy points to future challenges, promise

Advances in adapting the technology for cold climates and offshore use and better methods for predicting wind conditions have fanned significant growth of the use of wind turbines for electricity in the last 40 years. A new report takes stock of where the field is now and what lies ahead.

source https://techxplore.com/news/2019-08-growth-energy-future.html

Study: Naltrexone to treat opioid use disorder during pregnancy, favorable for mom, baby

BOSTON -Infants born to mothers taking naltrexone to treat opioid use disorder during pregnancy developed no signs of neonatal opioid withdrawal syndrome (NOWS) during their hospitalization, a new study shows. In comparison to infants of mothers taking buprenorphine during pregnancy, infants exposed to naltrexone had shorter hospital stays, and mothers reported no use of other opioids during their pregnancy. Led by researchers at Boston Medical Center, the findings provide important preliminary data on the outcomes for both mother and baby when naltrexone is used to treat opioid use disorder during pregnancy.

source https://medicalxpress.com/news/2019-08-naltrexone-opioid-disorder-pregnancy-favorable.html

Schrödinger's cat with 20 qubits

Dead or alive, left-spinning or right-spinning—in the quantum world particles such as the famous analogy of Schrödinger's cat can be all these things at the same time. An international team, including researchers from several leading American universities, together with experts from Forschungszentrum Jülich, have now succeeded in transforming 20 entangled quantum bits into such a state of superposition. The generation of such atomic Schrödinger cat states is regarded as an important step in the development of quantum computers which could outperform classical computers in solving certain tasks. The results were published in Science last Friday.

source https://phys.org/news/2019-08-schrdinger-cat-qubits.html

Gene for acid-sensitive ion channel identified

In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems. Special channels in the cell membrane selectively permit salt ions to flow in and out of cells. A research team led by Professor Thomas Jentsch at the FMP and MDC has now identified the molecular components of a previously unknown ion channel.

source https://phys.org/news/2019-08-gene-acid-sensitive-ion-channel.html

Poo's clues: Moose droppings indicate Isle Royale ecosystem health

Given the choice between ice cream and vegetables, for many people it'll be the ice cream. But sometimes it depends on the situation. If you'd eaten ice cream every day for a week, you might prefer the salad. Human preferences for different foods often depend on what's common fare and what's rare.

source https://phys.org/news/2019-08-poo-clues-moose-isle-royale.html

Cell biology: Compartments and complexity

Ludwig-Maximilians-Universitaet (LMU) biologists have taken a closer look at the subcellular distribution of proteins and metabolic intermediates in a model plant. The results of the study provide new insights into the dynamics of metabolic processes in cells.

source https://phys.org/news/2019-08-cell-biology-compartments-complexity.html

How plants synthesise salicylic acid

The pain-relieving effect of salicylic acid, now sold as Aspirin, has been known for thousands of years. Besides being a useful drug with numerous health applications, it is a stress hormone made by plants which is essential in enabling them to fight off damaging pathogens. What was not known, however, is how plants generated this hormone. Now, an international research team led by the University of Göttingen with the University of British Columbia in Vancouver have at last unravelled the biosynthesis of this crucial hormone. Their results were published in Science.

source https://phys.org/news/2019-08-synthesise-salicylic-acid.html

Fast, not so furious? Europe wrestles with electric scooters

Ban them outright. Issue speeding tickets. Make users take a driving test. From Paris to Berlin, European cities are searching for solutions to the two-wheeled phenomenon that's fast transforming cityscapes worldwide: Electric scooters.

source https://techxplore.com/news/2019-08-fast-furious-europe-electric-scooters.html