Wednesday 22 May 2019

After GWAS studies, how to narrow the search for genes?

Genome-wide association studies (GWAS) look at large populations to find genes that contribute to common, multi-gene traits like height or obesity. These comprehensive investigations frequently turn up large numbers of tiny genetic variations that show up more often in people who are tall, obese, etc. But this association doesn't mean the variant actually helps cause the trait; it could just be going along for the ride.

* This article was originally published here